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We reviewed over 20 different berberine supplements to compile a list of the 5 best choices for your weight loss, blood sugar, and cholesterol goals. This list looks at the Ingredients, Dosage, and Price Per Serving for each brand to determine the best berberine supplement of 2024. 

As we reviewed each berberine supplement, we considered three important factors:

• Ingredients: The very first thing we looked at was the ingredient label. For berberine, the ingredient label should tell us which plant(s) the berberine is sourced from. However, many berberine brands will vaguely put “Berberine HCL” on the supplement facts panel, without actually expanding on where the berberine was extracted from.

• Clinical Dosage: The clinical dosage for berberine is between 500 and 1,500 mg. With this in mind, we looked for berberine supplements that are within this range. Unfortunately, some berberine brands fall below this serving size, which may negatively impact the results you see from berberine.

• Price Per Serving: A berberine supplement should be affordable enough that you can purchase it for months and years to come. Yet, some supplements are so outrageously priced (like $52 for 30 servings) that you can barely afford to try them for a month. For that reason, we provide a “price per serving” for each supplement listed.

Berberine is a natural botanical that, just last year, made a resurgence in the natural health scene. 

Cultivated from flowering plants like barberry, goldenseal, and Oregon grape, berberine has been used for centuries to treat digestive issues, infections, and inflammation. But the latest research is showing that it can do a whole lot more…

Berberine Benefits: A 6-Month Timeline

By taking a potent berberine supplement daily, you may experience the following science-backed benefits:

• Lower blood sugar
• Reduced blood pressure and cholesterol levels
• Boosted metabolism
• Reduced cravings
• May prevent the formation of new fat cells
• Helps the body burn carbs (instead of storing them as body fat)
• Improved insulin sensitivity
• Anti-microbial and anti-inflammatory effects
• A healthy balance of gut bacteria
• Potential neuroprotective effects
• May protect liver health

Natural Reviews Top 5 Picks for 2024

from NativePath

Native Berberine features a unique 1,400 mg blend of three berberine-rich botanicals—Barberry, Goldenseal, and Oregon Grape. This is unlike any other berberine supplement on the market, most of which only have one form of berberine (usually from the Indian Barberry plant). Taking berberine daily can turn on what researchers call your “metabolic master switch,” helping you to achieve easier and faster weight loss, more balanced blood sugar, and more stable energy levels. For this reason, NativePath’s Native Berberine comes in at #1 on our list of 2024’s best berberine supplements. In addition to its pure and potent ingredients, this berberine supplement is also incredibly well priced, coming in at just $1.13 per serving—or as low as $0.73 per serving when purchased in bulk.

• 3-in-1 Blend of Berberine-Rich Botanicals

• All Natural Ingredients
• Promotes Easier Weight Loss
• Stabilizes Blood Sugar
• Helps Lower Cholesterol
• 100% Vegan, Gluten-Free, & Dairy Free

• No Fillers or Artificial Ingredients
• 30-Day Supply
• Easy-to-Take
• Bulk Discounts (+365-Day Money-Back Guarantee & Free Shipping)
• Third-Party Tested/Certificate of Analysis (COA)
• Made in USA

• Only Available Online

• Newly Launched Product (May Sellout Soon!)

NativePath's massive online fanbase makes taking Native Berberine more like being part of a healthy family than just buying a product. They are committed to the quality and effectiveness of their products and readily back up that commitment with a 365-day money-back guarantee. With their fantastic discounts, it's easy to stock up and save on premium products.

“I was pleasantly surprised that it actually works. I’ve lost 7 lbs in one month without a strict diet. My appetite is curbed and truly only eat when hungry. Give these a try.”

— Stephanie J, Verified NativePath Customer

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from Whitaker Nutrition

Securing the second spot on our list is Glucogold by Whitaker Nutrition. Developed by the pioneer of alternative medicine, Dr. Julian Whitaker, this unique formula includes 500 mg berberine HCL alongside three other blood sugar-supporting ingredients—cinnamon, banaba, and chromium. With its impressive roster of active ingredients, we were surprised to see that it has nine other “inactive” ingredients…including unnecessary fillers like cellulose, dicalcium phosphate, and glycerin. This, and the steep price ($52/bottle), is what dropped this brand to second place.

• 500mg Berberine HCL Per Capsule
• Derived from the Bark and Root of Indian Barberry
• Unique 4-in-1 Blend

• 90-Day Money Back Guarantee
• Third-Party Tested
• GMP (Good Manufacturing Practices) Certified

• Expensive (Double the price of our #1 Pick)
• Only Contains One Form of Berberine

• Contains 9 Filler Ingredients
• No Free Shipping

With a 20-year track record, Whitaker Nutrition has a high standard when it comes to the formulation and inspection of its supplements. This is evident from their Triple-Testing Philosophy™ and industry-leading Purity & Potency Check™. Despite these commitments, Glucogold ranks second due to its large number of inactive ingredients. In addition, the price is over double our first pick—Native Berberine.

from Solaray

Vital Extracts Berberine by Solaray ranks third on our list of 2024’s best berberine supplements. We appreciate Solary’s transparency in where their berberine is sourced from—the Indian Barberry shrub grown in the U.S. and Canada. However, a potential red flag is their inclusion of rice concentrate as a filler. This is concerning for a few reasons: rice (particularly brown rice) may contain trace amounts of arsenic. In addition, there could be a risk of cross-contamination with gluten, and some individuals may have an allergy or digestive sensitivity to rice.

• 500mg of Berberine HCL Per Capsule 
• Derived from the Root of Indian Barberry
• 100% Post-Consumer Recycled (PCR) Bottles
• Committed to Sustainability

• Affordable Price
• cGMP (Certified Good Manufacturing Practices)
• Made in USA (in Utah)
  

• Only One Form of Berberine
• Contains Whole Rice Concentrate (a filler)

• Potential for Allergic Reaction (from rice)
•  No Free Shipping

Solaray is our 3rd choice for berberine supplements. They’ve been a leading vitamin and mineral brand since 1973. Although crafted with good intentions, they missed the mark by adding whole rice concentrate to their berberine supplement.

from Sports Research

Coming in fourth on our list is Sports Research Berberine + Coconut Oil softgels. The addition of organic virgin coconut oil may enhance absorption, which we like. However, some customers complain that the softgels are too large and very hard to swallow. Since the brand recommends taking 2-3 capsules per day, this may be challenging (or nearly impossible) for some people to accomplish.

• 500 mg Berberine HCL Per Capsule
• Derived from the Bark of Indian Barberry
• Non-GMO

• Made with Organic Virgin Coconut Oil
• cGMP (Certified Good Manufacturing Practices)
• Third-Party Tested

• Contains Tree Nuts (Coconut)

• Very Large Softgels

• Some Users Report Nausea & Gastrointestinal Distress
• No Free Shipping

Sports Research has been a leading brand in sports nutrition for over 40 years. However, their large softgels and inclusion of coconut oil may be a turnoff for some people. For this reason, Sports Research dropped to fourth on our list of 2024’s best berberine supplements.

from NOW

Squeaking by on our list of best berberine supplements of 2024 is Berberine Glucose Support by NOW. At first glance, this supplement seems promising. It has 400 mg of berberine, plus MCT oil for optimal absorption, and it claims to support healthy glucose levels. But when you look under “Other Ingredients,” you’ll see a surprising addition: caramel color. 

Some concerns have been raised about certain types of caramel coloring and the potential presence of 4-methylimidazole (4-MEI), a chemical formed during its production that may be linked to an increased risk of cancer.

• 400 mg Berberine HCL Per Capsule
• Derived from the Bark of Indian Barberry
• Plus 700 mg MCT Oil

• cGMP (Certified Good Manufacturing Practices)
• 100% Post-Consumer Recycled (PCR) Bottles
• Free of Gluten, Dairy, & Soy

• Contains Carmel Coloring
• Very Large Softgel

• No Free Shipping

NOW’s Berberine Glucose Support comes in last on our list. Although a very reputable and well-known brand, the addition of caramel color was a huge letdown for us. In addition, the softgels are very large and may be difficult to take for some people.

Although it may look like it at first glance, no berberine supplement is the same.

When it comes down to it, there are three important characteristics to look for when shopping for berberine…

• Additional Ingredients: Some of the most popular berberine supplements are filled with unnecessary fillers like “rice concentrate” and potentially harmful colors like “caramel color,” amongst a whole slew of other ingredients. That said, be sure to triple-check the ingredient label before adding a berberine supplement to your shopping cart.

• Dose: Most berberine supplements contain 500 mg of berberine per capsule. This is common since manufacturers can’t squeeze 1,500 mg of berberine into a single-serving capsule. For this reason, you’ll want to make sure the berberine supplement contains at least 60 or 90 capsules (since you’re likely to be taking 2-3 capsules a day to maximize your health benefits).

• Brand Reputation: More than ever before, consumers need to do their due diligence before buying from a brand (which is why you’re here now, reading this blog!). It’s essential that your berberine supplement has a Certificate of Analysis (COA), is third-party tested, is produced in a Certified Good Manufacturing Practices facility, and is made right here in the USA. This will ensure it’s safe, pure, and potent—and up to industry standards. It’s also helpful to read reviews before purchasing any type of supplement.

All that said, be sure to talk with your doctor before adding a new supplement to your routine—especially if you have underlying health conditions or are taking medications. They can provide personalized advice based on your individual health profile.

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The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a health care provider. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any diseases or medical conditions. Results are based on the Natural Reviews Ranking System and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.

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